ProteinLMBench

944 manually checked multiple-choice questions on proteins, used to score LLMs on sequence and function understanding rather than to train them.

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Categorydomain
Subcategorymultiple-choice protein sequence and function understanding
Page statusactive
Metricaccuracy
Directionhigher_is_better
Unit%
Dataset size944
Dataset licenceApache-2.0
PublisherToursun Synbio, with Johns Hopkins University, University of Cambridge, Shanghai AI Laboratory, Shanghai Institute for Biomedical and Pharmaceutical Technologies, and Shanghai Jiao Tong University

What it measures

ProteinLMBench is a 944-item multiple-choice test of whether a language model understands proteins from sequence and text. Questions mix English protein facts with sequence-bearing items. They were drafted with retrieval-augmented generation and GPT-4, then passed through a two-round machine check and human verification; inconsistent items were dropped. The same paper also releases ProteinLMDataset (pretraining tokens and SFT instructions). That training set is not this benchmark. OpenCompass loads Hugging Face config `evaluation` only.

Task format

Six-choice multiple choice. The paper states 944 questions with six lettered options and an explanation of the correct answer. OpenCompass's default generator prompt asks for a final line `Answer: $LETTER` between the first and last option letters (the loader is generic over option count). A second OpenCompass config swaps in an LLM judge (GenericLLMEvaluator) instead of rule extraction.

Models reporting this benchmark

No model card in ModelSpec reports this benchmark yet.

Data

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