Mol-Instructions molecule-oriented tasks

An OpenCompass wrapper for six molecule-oriented Mol-Instructions tasks covering molecular descriptions, design, reactions, properties, and retrosynthesis.

Also known as: MolInstructions_chem, Mol-Instructions, OpenCompass MolInstructions chem

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Categorydomain
Subcategorymolecule-oriented biomolecular instruction evaluation
Page statusactive
MetricTanimoto similarity, mean absolute error, or METEOR by task
Directionhigher_is_better
Unittask-specific
Dataset size148400
Dataset licenceCC BY 4.0
PublisherZhejiang University NLP

What it measures

This benchmark evaluates instruction following for small-molecule chemistry. The molecule-oriented component contains molecule description generation, description-guided molecule design, forward reaction prediction, retrosynthesis, reagent prediction, and property prediction. Inputs use SELFIES in the OpenCompass configuration and outputs are molecular strings, numbers, or natural-language descriptions.

Task format

Zero-shot generation. OpenCompass formats each task with a chemistry system prompt and asks for SELFIES tags for molecular outputs, a boxed number for property prediction, or natural language for descriptions. It evaluates molecular outputs with Morgan-fingerprint Tanimoto similarity, numbers with MAE, and descriptions with METEOR.

Models reporting this benchmark

No model card in ModelSpec reports this benchmark yet.

Data

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